Use the medicine exactly as directed. Version: 8.01. Revised: November, 2021 PT 2859-01, NDC 67877-558-17BrompheniramineMaleate,PseudoephedrineHydrochloride andDextromethorphanHydrobromide SyrupEach 5 mL (teaspoonful) contains:Brompheniramine Maleate, USP 2 mgPseudoephedrine Hydrochloride, USP 30 mgDextromethorphan Hydrobromide, USP 10 mgAlcohol 0.95% v/v Rx Only NET: 4 fl oz (118 mL) Ascend Laboratories, LLC, NDC 67877-558-16BrompheniramineMaleate,PseudoephedrineHydrochloride andDextromethorphanHydrobromide SyrupEach 5 mL (teaspoonful) contains:Brompheniramine Maleate, USP 2 mgPseudoephedrine Hydrochloride, USP 30 mgDextromethorphan Hydrobromide, USP 10 mgAlcohol 0.95% v/v Rx Only NET: 1 Pint (473 mL) Ascend Laboratories, LLC, Report Adverse Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold. Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). You may report side effects to your national health agency. Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Examples of these blood pressure drugs include: Disclaimer: Our goal is to provide you with the most relevant and current information. This includes isocarboxazid, phenelzine, or tranylcypromine. You should not need a new prescription for this medication to be refilled. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. You must check to make sure that it is safe to give this drug with all of your childs other drugs and health problems. This drug is a combination of three drugs in a single form. this version. If your symptoms are severe, call 911 or go to the nearest emergency room right away. show all 41 brands Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis. This drug may make you more sensitive to the sun. Pseudoephedrine is a decongestant. In addition, MAO inhibitors prolong and intensify theanticholinergic (drying) effects of antihistamines and may enhance the effect of pseudoephedrine. Bromfed DM is available only with a prescription and comes as a liquid. Tell the doctor and pharmacist about all of your childs drugs (prescription or OTC, natural products, vitamins) and health problems. Some items may interact with your medicine. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. In young children, this drug can cause excitation instead of drowsiness or sedation. System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. Terms of Use. COMMON BRAND NAME(S): Anaplex, Anaplex DM, Andehist DM, Andehist DM NR, Brom/PSE/DM Cough, Bromaline DM, Bromatane DX, Bromaxefed DM RF, Bromdex D, Brometane DX, Bromfed-DM, Bromophed DX, Bromphenex DM, Bromplex DM, Brotapp-DM, BroveX PSB DM, Carbofed DM, Cardec DM, Dallergy DM, Decon DM, Dimetane DX, Dimetapp Children's DM Cold and Cough, Dynatuss, EndaCof-DM, LoHist PSB DM, Myphetane DX, Neo DM, PBM Allergy, Q-Tapp DM, Robitussin Cough and Allergy, Rondamine DM, Rondec DM, Sildec DM, Tuss Mine DM. It may contain 10% sodium citrate solution for pH adjustment. For more resources, visit www.mskcc.org/pe to search our virtual library. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Pseudoephedrine acts on sympathetic nerve endings and also on smooth muscle, making it useful as a nasaldecongestant. Use only as directed. Antihistamines appear to compete with histamine for receptor sites oneffector cells. is this? For people with heart disease: You shouldnt use pseudoephedrine, one of the ingredients in this drug, if you have severe heart disease. Pseudoephedrine belongs to a class called vasoconstrictors. Avoid becoming overheated or dehydrated during exercise and in hot weather. It should only be used as needed. Following oral administration, effects arenoted within 30 minutes with peak activity occurring at approximately one hour. Avoid driving or hazardous activity until you know how this medicine will affect you. This drug is used for short-term treatment. Be sure to avoid doing this when the weather is very hot or very cold. Infants 6 months to under 2 years of age: Dosage to be established by a physician. Drug information contained herein may be time sensitive. Put it in the trash. Do not use the medicine to make a child sleepy. Talk to your doctor about whether this drug is safe for you. For this drug to work well, a certain amount needs to be in your body at all times. Check with your pharmacist if you have questions about the best way to throw out drugs. To help avoid interactions, your doctor should manage all of your medications carefully. Alcohol is not needed in the recipe to experience these benefits. Brompheniramine-dextromethorphan-pseudoephedrine oral syrup can interact with other medications, vitamins, or herbs you may be taking. Should CNS hyperactivity or convulsive seizures occur, intravenous short-acting barbiturates may be indicated. Hypertensive responses and/or tachycardia should be treated appropriately. July 27, 2022. Brompheniramine, Pseudoephedrine, and Dextromethorphan, All rights owned and reserved by Memorial Sloan Kettering Cancer Center, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. Because of its antihistamine component, brompheniramine maleate, pseudoephedrine hydrochloride anddextromethorphan hydrobromide syrup should be used with caution in patients with a history of bronchialasthma, narrow angle glaucoma, gastrointestinal obstruction, or urinary bladder neck obstruction. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.Like the other first-generation drugs of its class, it is considered a sedating antihistamine. This information is not a substitute for medical advice. RECOMMENDED STORAGE Learn why this popular myth exists and why whiskey isn't an, Learn about a variety of sore throat natural remedies, from honey to gargles to the hot toddy. Brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide syrupis a clear, light pink syrup with a butterscotch flavor. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. Concomitantadministration of brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide syrup and MAO inhibitors shouldbe avoided (see CONTRAINDICATIONS). asthma or COPD (chronic obstructive pulmonary disease); a cough with mucus, or a cough caused by smoking, asthma, or emphysema; a blockage in your digestive tract (stomach or intestines); a bladder obstruction or other urination problems; Follow all directions on your prescription label and read all medication guides or instruction sheets. Naloxone hydrochloride 0.005 mg/kg intravenously may be of value in reversing the CNS depression that may occur from an overdose of dextromethorphan. Using this drug increases your risk of an abnormal heart rhythm, heart attack, stroke, and cardiac arrest. Gastric lavage may be carried out, although in someinstances tracheostomy may be necessary prior to lavage. Sympathomimetic may reduce the effects of antihypertensive drugs. To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. Brompheniramine/dextromethorphan/PSE 4 mg-20 mg-40 mg oral tablet: 1 tablet orally every 4 to 6 hours not to exceed 6 tablets daily. You should not use this medicine if you are allergic to it brompheniramine, dextromethorphan, or pseudoephedrine, or if you have: severe coronary artery disease (clogged arteries). G.U. Brand names: Allanhist PDX Drops, Anaplex DM, Andehist DM NR Syrup, Bromaline DM, Bromhist PDX, Add Resources to Your List. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Take 5 mL (1 teaspoon) once every 4 hours. Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide. If theyre more severe or dont go away, talk to your doctor or pharmacist. Read all information given to you. BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE syrup, 0574-1104-04, Misuse of this medicine may cause death in very young children. This information from Lexicomp explains what you need to know about this medication, including what its used for, how to take it, its side effects, and when to call your healthcare provider. Brompheniramine, one of the ingredients in this drug, may cause drowsiness. This can make it harder to breathe. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This includes your childs doctors, nurses, pharmacists, and dentists. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. This copyrighted material has been downloaded from a licensed data provider. Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, If you have any questions, contact a member of your care team directly. You may report side effects to FDA at 1-800-FDA-1088. However, antihistamines are more likely to causedizziness, sedation, and hypotension in elderly patients. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car oroperating dangerous machinery. Hypersensitivity to any of the ingredients. 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