Because PTH exhibits an exaggerated response to any calcium, it is not considered a valid measurement by researchers in bone health. I thought I was doing everything right. Your advice would be much appreciated. I am presently taking New Chapter Bone Strength Take Care. Women using HRT were shown to have higher BMD and also greater risk of breast cancer. Luckily, strontium has science to back it up and someone (i.e. Teenagers 14-18 years: 15 micrograms (600 IU) Of course, happy to do what I can to be of help, and yes, each of us is our own best advocate, although you are definitely in good hands if you are working with a fully IFM certified functional medicine physician and nutritionist. So, if your patient achieves a 5% increase in BMD in their lumbar spine, when you factor out strontiums BMD overestimation, on average thats still a 4.5% increase. 2012 Oct;33(10):1277-84. doi: 10.1038/aps.2012.83. By staggering your intake, you allow both supplements to be absorbed properly and effectively. From AlgaeCal site: Myth #3 Strontium Skews DEXA Results too much to be reliable: Hope you will let me know how your DXA turns out. Hi Todd, In my opinion, if all webmasters and bloggers made just right content as you did, the net will probably be much more useful than ever before. I am confused what dose I should now be using. Who can I ask about the optimal frequency of DEXA tests so I am properly monitoring my bone density? The time, effort, and knowledge which you apply to answering questions is amazing. What I can offer you are some suggestions in response to what I see in your note to me this will sound like an advertisement, but I urge you to get a copy of Your Bones and read it! AlgaeCal Plus provides 720 mg of plant-based calcium and the average western diet provides another 500 mg. AlgaeCal Plus provides 1,600 iu of D3 daily, but some of us need more depending upon where we live (latitude impacts our ability to produce vitamin D from sun exposure) and our genetic inheritance, which can greatly affect our ability to maintain healthy levels of vitamin D, which, for 25(OH)D, should be in the range of 50-80 ng/mL. Human beings cannot properly fully digest gluten even if no apparent digestive upset occurs, it still is provoking at least 5 different and very nasty immune system reactions, plus causing a leaky gut. These exercises can help you strengthen the muscles that support your spine, so can help you to decompress and re-elongate your spine. We dont have it yet though. Modeling elemental strontium in human bone based on in vivo x-ray fluorescence measurements in osteoporotic females self-supplementing with strontium citrate. not writing a paper, thats for sure. Would love to find a Bastry U. grad here that you guys knew. Start now. You want both of these to be used inside your body the strontium, to build bone, and the citrate, to help make your overall pH more alkaline. PLEASE ANY IFO WOULD BE GREAT SHES SCARED AND HEARTBOKEN, Hello Amanda, AlgaeCal is a pure algae product / for Aquamin, *80% of material brought on to the large dredgeing ship is discarded as impure Lara. Urinary strontium and the risk of breast cancer: a case-control study in Guangzhou, China. I only have (1) one kidney so should I take the 2 supplements? If you are not allergic to dairy foods, then I expect you are likely getting at least several hundred milligrams of calcium from milk, cheese, yogurt, kefir, etc. After about 2 weeks I noticed extreme fatigue. Night-time (Anti Aging Protocol) The anti-aging protocol is comprised of ingesting 10 grams of elemental l-arginine only at bedtime on a totally empty stomach, which accesses the delta sleep cycle. I am so so worried and keep awake the whole night. Although you only need 3 milligrams of boron daily, this is a trace mineral that is difficult to get even in that small amount from the diet. Lara. Re the inflammation (which as you know promotes activation of osteoclasts, so we really need to get that down! Factors that raise a womans GAIL score are starting menstruation early (so more exposure to estrogens), age at first live birth (pregnancy and nursing lowers estrogen exposure for at least a year, longer if nursing), number of breast biopsies (checking b/c of indications of breast cancer), a history of atypical hyperplasia (abnormal excessive replication of breast tissue cells), and a history of lobular carcinoma in situ (breast cancer). And this applies to ANYTHING you see on the web. I do have Hashimotos and have been on a compounded T3 for over 20 years. I just had another Dexa Scan as Ive had 2 fractures on each ankle in last 4-5 years and am terribly disappointed to find a slight fall in score. A creatinine clearance rate of 60-89 indicates the initial stage of kidney disease. I have found what works is 2 Algae Cal at breakfast, 1 at lunch, and 1 at dinner and all is well. Let me know how your personal clinical trial turns out, and Be well! So, my first question for you is, Are you taking your AlgaeCal Plus & Strontium Boost on an empty stomach? Let me know how she is doing, Lara, I was taking 680 strontium citrate, 1130 calcium and 450 magnesium citrate. Strontium is best taken at night at least two to three hours after a meal or any calcium. I take at night on an empty stomach & within a short amount of time I have very loose stools. These techniques were applied on bone mineral samples obtained from the iliac crest of male cynomolgus monkeys treated for 13 weeks with oral doses of strontium ranelate. Lis thesis also very nifty I am assuming this was animal research, so results would need to be confirmed in human trials, but his suggestion that calcium will supply nutrition for bone while strontium will display synergistic effects for enhancing bone formation activity and confirmation via the finding that Oral administration of strontium fortified calcium compound significantly increased expression of IGF-I and Runx2 in bone matrix. The other study cited (Korpelainen et al.) These nutrients are FOOD for your bones. Reading your book and following all your posts has really helped me. A 4 hour separation is ideal, however as long as there is at least a 2 hour separation between strontium and calcium you can take it at any time of the day so taking your breakfast smoothie 2 hours later would be sufficient. The most common stable strontium salts are strontium sulfate and strontium carbonate,which are found in soils, and strontium citrate which is used for nutritional supplements. In addition I take 5 mg of Vitamin K4 (menatetrenone). Strontium has nearly twice the atomic weight of calcium. Strontium carbonate notably is found in cathode ray tubes in old television sets. for vitamin D is 400 IUs and the plain and plus give 1000 IUs and 800 IUs respectively, but they both say they deliver 100% of the D.V., shouldnt it say 250% and 200% correspondingly? Every woman in my family whom I know about for many generations back died from osteoporosis I am the poster child for risk for this disease, but have managed to beat it by learning what my bones need and supplying it. I am intrigued by all this information. Eventually, I expect we will be able to get our full genetic template. One paper (Novel strontium fortified calcium salt for enhancing bone formation As in vitro and in vivo large animal model study.) Just curious if others are taking their strontium with or without food. Aquamin has done one absorption study where PTH response is measured. https://www.progressivenutritional.com/products/multivitamin-for-women-50. I eat the calcium-dense foods (e.g., yogurt, goat cheese, cottage cheese, soymilk enriched with calcium, tofu, spinach) at breakfast and dinner. 16/04/2012 18:14. take strontium citrate and calsium ect.. i changed to strontium citrate [ costs about a third of ranelate]about 3months ago after being on ranelate for 5years.. i had a bmd in january and it showed a small improvement which i am grateful for i`m 63yrs and excited to see next year`s results i am changing my calsium from Biogen Calmag Max Absorption[with120ug K2 ect to Real Thing Bone Revolution an organic sea veg calsium mineral mix these products we get in south africa.. further i take everthing in stride,,, had a couple of falls with no fractures perhaps i`m just lucky referring to other letters of people having a lot of fractures nice writing to you forgive the errors, english is my second language regards.. patricia. The combination of all 3 is synergistic. Or do you half that too? I found the referenced study, with its PMID #, for you. What schedule can help me optimize strontium absorption and let me lead a normal life? (Moise H, Adachi JD, Chettle DR, et al. Heres the math on this: 1.04% x .915 (100%-8.5% = 91.5) = an increase in BMD of 0.95. It has been suggested that bone resorption is most active at night, so taking strontium citrate just before bed may result in strontium exerting more of its antiresorptive effects when they are needed most. Thus, for 71% of the participants in this study, a short daily period of exercise, a few minutes of which was high impact exercise, was a reasonable and safe recommendation. AlageCal is harvested sustainably as evidenced by IBD and IBAMA / Aquamin is not sustainable as evidenced by their move from Ireland to Iceland for harvesting The study to which you sent me a link is the only human study I could find, but recent papers indicate lactoferrin may be quite helpful. Thanks for your response about New Chapter. There are only 360 mg of calcium in the two tablets listed as serving size. Optimal intake is 1,2 1,500 mg per day for someone with osteoporosis. And you do. Ideally an hour before, or three hours after eating. "He didn't do it. alternatively, is there a vegetable that I could substitute the kale for to put in my smoothie that is low in calcium so I could take with the strontium? Im counting on Strontium Boost (and AlgaeCal Plus) to keep my bones in good shape for my, as yet, non-existent grandchildren. Since you are getting 100 mcg from your other supplements, if you just took the full dose of AlgaeCal Plus, you would be getting 190 mcg/day. I have Your Bones on my Kindle now so I am reading (but must admit at my age I do forget rather quickly so sometimes need to re-read..) How did your DEXA tests turn out after being on AlgaeCal? None of the articles however, showed 170 mg to be more effective than 680 mg. I no longer have this problem because I treated the reasons for this pain primarily by increasing my intake of anti-inflammatory omega-3s. Mitigation of bone loss with ultrasound induced dynamic mechanical signals in an OVX induced rat model of osteopenia. No worries it took me months to figure this out. If you still have symptoms at this half dose, please ask your doctor about running a CDSA (Comprehensive Digestive Stool Analysis) or the OAT (a far more comprehensive test, the Organic Acids Test) to check whats in your gut. (The creatinine clearance rate is also called the glomerular filtration rate because tiny capillaries in the basic structural and functional unit of the kidney, the nephron, are called glomerular capillaries. COMPETITION BETWEEN CALCIUM, STRONTIUM, AND MAGNESIUM FOR ABSORPTION IN THE ISOLATED RAT INTESTINE.Clin Chem. Please advice. In contrast, the MK-7 form remains bioactive in the body for about 3 days this is one of the key reasons why you need so much less just 120 mcg has been shown in the research to be effective for MOST people. Strontium citrate is not a medication and we dont anticipate that it would have contributed to the development of lymphocytic colitis. Lara Just prefer not to take anything that may have side effects. Ill quote them: strontium may interact with estrogens to promote carcinogenesis among young [premenopausal] women, because young women have more estrogens and estrogen receptors., Chen LJ, Tang LY, He JR, et al. Am insurance poor, so have to go to conventional doctors. Nonetheless, from the papers I have read, 170 mg of elemental strontium has not been shown to be more effective in rebuilding bone although even the longer studies looked at no more than 2 years if I remember correctly. For most of us, its at least 400 mg /day. Taking strontium supplements for any period of time is likely to make future bone density tests inaccurate. Hi SML, I am happy to suggest some choices of natural strontium supplements for you. Read more about Phytates & Calcium Absorption. The optimal duration of use of Boniva has not been determined. Bottom Line for best absorption, take strontium separately from other minerals. Hi Lara MANY people are deficient in iodine for a variety of reasons I summarized in a 2 part review paper I wrote on iodine for Longevity Medicine Review (here is a link to Part I http://www.lmreview.com/articles/view/iodine-the-next-vitamin-d-part-I/) As I expect you know, our bodies cannot produce thyroid hormone without sufficient iodine (T4 requires 4 iodine molecules, T3 requires 3 of them). So its incorporation of strontium which is less than 1 strontium ion for every 100 calcium ions even in trabecular bone is even less than cortical bone. Expression profiles of transporters and metabolizing enzymes in both rat and human intestines (duodenum and colon) were measured using GeneChip analysis. Strontium citrate is also very safe, again, no adverse effects have been seen with natural forms of strontium (ie strontium citrate) if more calcium is being consumed than strontium. I remember when my mother was dying from hip fracture + congestive heart failure along with my 23 year old cat, who we were giving fluids several times a day because of her kidney failure I was so stressed out and sad that I lost TONS of hair. Ranelic acid is the synthetic compound used to create the unnatural strontium salt, strontium ranelate. Also I find the lower dosage of calcium in AlgaeCal Plus to be more appealing than the plain (360 mg compared to 750 mg); however, I do wonder why does it contain so little calcium relative to the given dosage of strontium; it appears, from the studies and recommendations given on this website, that calcium intake should be greater than that of strontium intake? By 120 h, the increase was statistically significant at 0.68 0.07 and 0.93 0.05, respectively. Hi Alice, What is an adequate amount is for post-menopausal women to take? This is what I do for myself. Sr21 is taken up into bone by two different mechanisms: (1) an initial rapid mode, depending on osteoblastic activity, which is eventually saturated, and whereby Sr21 is taken up by ionic exchange with bone Ca21, binding of Sr21 to preosteoid proteins, or combinations of these; and (2) a second slower mechanism involving the incorporation of Sr21 into the crystal lattice of the bone mineral. This type of pain in your thumb is not due to strontium; it indicates arthritis in the joint. Thank you for all your help, will run that info by the allergist, and also check with GYN-possibly DHEA could help. Could you comment on the possibility that strontium citrate can promote hair loss? Therapeutically, radioactive strontium is used to treat metastatic cancer but can damage bone marrow and act as a potential carcinogen itself at high doses. Taking your thyroid medication properly helps you absorb it well and limits your risk of side effects. Secondly, if you stop taking strontium, do you experience accelerated bone loss or does it stay in the bone. These are the 4 and 16alpha -OH compounds derived from estrogen, which are pro-inflammatory. Im not sure where I should look for a response. Australia truly one of the loveliest places on Earth. I am just now going back over all the research on strontium and will be posting a full article on all this in the very near future. If you end up finding your vit D3 needs run even higher to 10,000 IU/day you could check out Life Extensions vitamin K supplement, which is what I use for my additional K2 since I must take 10,000 IU/day of D3. http://www.lmreview.com/articles/view/select-the-right-hormone-test-for-your-patient-using-bio-identical-hormone-/ I found your product and started taking it this week, however when I take the Strontium at night, I get this weird pain in my right thumb, where the thumb joins the hand and I cant use it to lift anything it is very weird. Combined with X-ray diffraction and secondary Raman spectroscopic images, it was demonstrated that strontium was dose-dependently taken up by the bone mineral and heterogeneously distributed in compact and cancellous bone, with a higher amount in newly formed bone tissue than in old bone tissue. I have a lot less coughing for no apparent reason. Cortical bone is their hard, outer layer. 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